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Hepatitis B and C coinfection linked to worse fibrosis than hepatitis B alone

People coinfected with both hepatitis B virus (HBV) and hepatitis C virus (HCV) may experience more rapid and severeLIVER DISEASE progression than those with hepatitis B alone, though HBV/HCV coinfection did not appear to worsen hepatitis C progression, according to a French study presented at the European Association for the Study of the Liver (EASL) […]

Many Cancer Patients at Risk for Hepatitis B Virus Reactivation

In 2015, no cancer patients should be cured of their malignancy only to die of reactivation of hepatitis B virus (HBV),” according to Anna S. Lok, MD, the Alice Lohrman Andrews Research Professor in Hepatology and Director of Clinical Hepatology at the University of Michigan, Ann Arbor. “I recommend screening all patients before starting on […]

Oral hepatitis B vaccine could become a reality

In a new study, researchers report progress toward perfecting a radical new method of producing vaccines using genetically modified corn. The approach could lead to an oral hepatitis B vaccine that requires no refrigeration and costs less than $1 per dose to manufacture. “Even though an effective injectable hepatitis B vaccine was developed more than […]

WHO issues its first hepatitis B treatment guidelines

12 MARCH 2015 ¦ GENEVA – WHO today issued its first-ever guidance for the treatment of chronic hepatitis B, a viral infection which is spread through blood and body fluids, attacking the liver and resulting in an estimated 650 000 deaths each year – most of them in low- and middle-income countries. Worldwide, some 240 […]

Eric Abidal: Despite the disease, there is always hope

LIVING WITH LIVER DISEASE In 2011, French footballer Eric Abidal learnt he had cancer of the liver. Despite the disease, he carried on with his career, sending out a real message of hope for all those people who are battling cancer. How did you find out you had the disease? Eric Abidal – “I was really […]

Top tips for a healthy liver from United European Gastroenterology

THE FACTS Professor Manns gives his top five tips on how to reduce your risk of developing liver cancer United European Gastroenterology Vice President and consultant gastroenterologist, Professor Michael Manns, explains, “There is a need to develop specific therapies for the treatment of patients with alcoholic liver disease, especially as it is the second LEADING […]

Seeing past the stigma of cirrhosis

LIVING WITH LIVER DISEASE Cirrhosis carries a stigma, but this liver disease in not always the result of alcohol or drug use, and early diagnosis and treatment can help the liver to heal itself Cirrhosis is commonly assumed to be the result of alcoholism or intravenous drug use – but this is not always the […]

Campaign against liver disease

THE FUTURE Government must act on liver deaths, say doctors Professor Roger Williams, Director of the Institute of Hepatology, Foundation for Liver Research, says: “Deaths from liver disease are rising in the UK, but government resistance means we have achieved none of the recommendations of a recent Lancet report.” The report called for improved early […]

The killer that everyone’s been ignoring

THE FACTS Globally viral hepatitis causes almost 7 times as many liver cancer deaths as alcohol use but lack of awareness leaves this global killer vastly ignored Now the second biggest cancer killer worldwide, liver cancer is undeniably a significant global issue. A staggering 78% of all liver cancer deaths are caused by viral hepatitis […]

A New Approach to Hepatitis B Therapy?

Cyclophilins are involved in multiple steps of the hepatitis B virus (HBV) life cycle in hepatocytes—cyclophilin inhibitors reduce viral replication and HBV envelope protein production and secretion, researchers report in the February issue of Gastroenterology. The cyclophilin inhibitor alisporivir, combined with the HBV polymerase inhibitor, reduces markers of HBV infection and HBV replication in cells, […]